The global high-affinity nerve growth factor receptor market is anticipated to grow at a significant CAGR of 5.4% during the forecast period 2022-2028. Nerve growth factor (NGF) is a protein that resembles insulin. The rising prevalence of cancer around the globe is a primary factor driving market expansion. For instance, as per the information provided by the American Cancer Society, Inc., the estimated numbers of new cancer cases diagnosed were around 1.8 million and deaths in the US were nearly 606,520 in 2020. Aside from that, NGF exerts its effects in atopic dermatitis by attaching to two types of transmembrane receptors: high-affinity and low-affinity receptors. So, the rising frequency of atopic dermatitis is driving demand for high-affinity nerve growth factor receptors, which play a key role in the treatment of atopic dermatitis such as skin lesions and, as a result, the market is growing.
Impact of COVID-19 Pandemic on Global High-Affinity Nerve Growth Factor Receptor Market
The COVID-19 Pandemic had a significant impact on the global high-affinity nerve growth factor receptor market. The COVID-19 infection in patients can be cured with the treatment of nerve growth factors. In order to treat a COVID-19 patient, high-affinity nerve growth factor receptor has been used heavily, which has supported the market to grow. The demand for the drugs and therapeutics during the COVID-19 increased significantly. As a result, the market saw an inclination as an impact of COVID-19.
Segmental Outlook
The global high-affinity nerve growth factor receptor market is segmented based on drug type and application. Based on the drug type, the market is sub-segmented into ASP-7962, AZD-7451, BNN-27, cenegermin, CRB-0089, and others. Based on the application, the market is sub-segmented into atopic dermatitis, cancer, and others.
Global High-Affinity Nerve Growth Factor Receptor Market Share by Application, 2021 (%)
The Atopic Dermatitis Segment is Anticipated to Hold a Prominent Share in the Global High-Affinity Nerve Growth Factor Receptor Market
The atopic dermatitis segment is forecasted to hold a prominent share in the market during the forecast period due to the increasing prevalence of atopic dermatitis globally. According to the National Institute of Allergy and Infectious Disease, atopic dermatitis is an inflammatory skin condition that affects an estimated 30% of the US population, mostly children and adolescents. Apart from that, nerve growth factor works in atopic dermatitis by binding to two different types of transmembrane receptors: high-affinity and low-affinity receptors. As a result, demand for high affinity nerve growth factor receptors is increasing as the prevalence of atopic dermatitis rises.
Regional Outlooks
The global high affinity nerve growth factor receptor market is further segmented based on geography including North America (the US, and Canada), Europe (UK, Italy, Spain, Germany, France, and Others), Asia-Pacific (India, China, Japan, and Others), and the Rest of the World (the Middle East & Africa, and Latin America). Increasing advancements in technology in emerging economies of the region are likely to drive the growth of the regional market. Further, rising health care expenditure along with increasing research and development activities in India, China and South Korea are also some of the factors that are affecting and impacting the growth in this market.
Global High-Affinity Nerve Growth Factor Receptor Market Growth, by Region 2022-2028
The North America Region is Estimated to Hold the Prominent Share in the Global High-Affinity Nerve Growth Factor Receptor Market
Throughout the projected period, North America is expected to have a significant share in the global high-affinity nerve growth factor receptor market. The region's significance is attributable to a number of causes, including a rising senior population that is more susceptible to illnesses due to decreasing immunity, resulting in high demand for effective medication. The rising cases of atopic dermatitis in the North American region are propelling the growth of the market. Additionally, the presence of the major players in the region is aiding in the growth of the market as the research and development activities are taking place.
Market Players Outlook
Astellas Pharma Inc., Pfizer Inc., and Merck & Co Inc. are some of the market's leading participants. To stay competitive in the market, industry players are using a variety of strategies such as mergers and acquisitions, regional expansion, partnerships and collaborations, and new product releases to contribute substantially to market growth. For instance, in January 2020, Pfizer inc. and Lilly collaborated and submitted a Tanezumab application to the US Food and Drug Administration (FDA). At the lower 2.5mg dosage, it is a first-in-class NGF inhibitor for the treatment of osteoarthritis pain.
The Report Covers
1. Report Summary
1.1. Research Methods and Tools
1.2. Market Breakdown
1.2.1. By Segments
1.2.2. BY Region
2. Market Overview and Insights
2.1. Scope of the Report
2.2. Analyst Insight & Current Market Trends
2.2.1. Key Findings
2.2.2. Recommendations
2.2.3. Conclusion
3. Competitive Landscape
3.1. Array BioPharma Inc.
3.1.1. Overview
3.1.2. Financial Analysis
3.1.3. SWOT Analysis
3.1.4. Recent Developments
3.2. Astellas Pharma Inc.
3.2.1. Overview
3.2.2. Financial Analysis
3.2.3. SWOT Analysis
3.2.4. Recent Developments
3.3. AstraZeneca PLC
3.3.1. Overview
3.3.2. Financial Analysis
3.3.3. SWOT Analysis
3.3.4. Recent Developments
3.4. Daiichi Sankyo Co. Ltd.
3.4.1. Overview
3.4.2. Financial Analysis
3.4.3. SWOT Analysis
3.4.4. Recent Developments
3.5. Dompe Farmaceutici SpA
3.5.1. Overview
3.5.2. Financial Analysis
3.5.3. SWOT Analysis
3.5.4. Recent Developments
3.6. Key Strategy Analysis
3.7. Impact of Covid-19 on Key Players
4. Market Segmentation
4.1. Global High Affinity Nerve Growth Factor Receptor Market by Drug Type
4.1.1. ASP-7962
4.1.2. AZD-7451
4.1.3. BNN-27
4.1.4. Cenegermin
4.1.5. CRB-0089
4.1.6. Others
4.2. Global High Affinity Nerve Growth Factor Receptor Market by Application
4.2.1. Atopic Dermatitis
4.2.2. Cancer
4.2.3. Others
5. Regional Analysis
5.1. North America
5.1.1. United States
5.1.2. Canada
5.2. Europe
5.2.1. UK
5.2.2. Germany
5.2.3. Italy
5.2.4. Spain
5.2.5. France
5.2.6. Rest of Europe
5.3. Asia-Pacific
5.3.1. China
5.3.2. India
5.3.3. Japan
5.3.4. Rest of Asia-Pacific
5.4. Rest of the World
6. Company Profiles
6.1. Akeso, Inc.
6.2. Genzyme Corp.
6.3. Handok Inc.
6.4. Ignyta Inc.
6.5. Kyowa Kirin Co., Ltd.
6.6. Loxo Oncology Inc.
6.7. Merck & Co. Inc.
6.8. Nerviano Medical Sciences Srl
6.9. Pfizer Inc.
6.10. Plexxicon Inc.
6.11. Proximagen Ltd.
6.12. Rottapharm Biotech Srl
6.13. Sienna Biopharmaceuticals Inc.
6.14. Tiziana Life Sciences PLC
1. GLOBAL HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY DRUG TYPE, 2021-2028 ($ MILLION)
2. GLOBAL ASP-7962 HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
3. GLOBAL AZD-7451 HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
4. GLOBAL BNN-27 HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
5. GLOBAL CENEGERMIN HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
6. GLOBAL CRB-0089 HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
7. GLOBAL OTHERS HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
8. GLOBAL HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY APPLICATION, 2021-2028 ($ MILLION)
9. GLOBAL ATOPIC DERMATITIS HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
10. GLOBAL CANCER HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
11. GLOBAL OTHERS HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
12. GLOBAL HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY GEOGRAPHY, 2021-2028 ($ MILLION)
13. NORTH AMERICAN HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2021-2028 ($ MILLION)
14. NORTH AMERICAN HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY DRUG TYPE, 2021-2028 ($ MILLION)
15. NORTH AMERICAN HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY APPLICATION, 2021-2028 ($ MILLION)
16. EUROPEAN HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2021-2028 ($ MILLION)
17. EUROPEAN HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY DRUG TYPE, 2021-2028 ($ MILLION)
18. EUROPEAN HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY APPLICATION, 2021-2028 ($ MILLION)
19. ASIA-PACIFIC HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2021-2028 ($ MILLION)
20. ASIA-PACIFIC HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY DRUG TYPE, 2021-2028 ($ MILLION)
21. ASIA-PACIFIC HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY APPLICATION, 2021-2028 ($ MILLION)
22. REST OF THE WORLD HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2021-2028 ($ MILLION)
23. REST OF THE WORLD HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY DRUG TYPE, 2021-2028 ($ MILLION)
24. REST OF THE WORLD HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY APPLICATION, 2021-2028 ($ MILLION)
1. GLOBAL HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY DRUG TYPE, 2021-2028 ($ MILLION)
2. GLOBAL ASP-7962 HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
3. GLOBAL AZD-7451 HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
4. GLOBAL BNN-27 HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
5. GLOBAL CENEGERMIN HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
6. GLOBAL CRB-0089 HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
7. GLOBAL OTHERS HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
8. GLOBAL HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY APPLICATION, 2021-2028 ($ MILLION)
9. GLOBAL ATOPIC DERMATITIS HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
10. GLOBAL CANCER HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
11. GLOBAL OTHERS HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)
12. GLOBAL HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY GEOGRAPHY, 2021-2028 ($ MILLION)
13. NORTH AMERICAN HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2021-2028 ($ MILLION)
14. NORTH AMERICAN HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY DRUG TYPE, 2021-2028 ($ MILLION)
15. NORTH AMERICAN HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY APPLICATION, 2021-2028 ($ MILLION)
16. EUROPEAN HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2021-2028 ($ MILLION)
17. EUROPEAN HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY DRUG TYPE, 2021-2028 ($ MILLION)
18. EUROPEAN HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY APPLICATION, 2021-2028 ($ MILLION)
19. ASIA-PACIFIC HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2021-2028 ($ MILLION)
20. ASIA-PACIFIC HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY DRUG TYPE, 2021-2028 ($ MILLION)
21. ASIA-PACIFIC HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY APPLICATION, 2021-2028 ($ MILLION)
22. REST OF THE WORLD HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2021-2028 ($ MILLION)
23. REST OF THE WORLD HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY DRUG TYPE, 2021-2028 ($ MILLION)
24. REST OF THE WORLD HIGH-AFFINITY NERVE GROWTH FACTOR RECEPTOR MARKET RESEARCH AND ANALYSIS BY APPLICATION, 2021-2028 ($ MILLION)