Neprilysin Market

Global Neprilysin Market Size, Share & Trend Analysis Report by Type (TD-0714, Sacubitril, PL-265, STR-324, and LHW-090), by Application (Acute Heart Failure, Cancer Pain, Hypertension, and Alzheimer’s Disease), Forecast (2022-2028)
    Update Available - Forecast 2024-2030   

Published: Jul 2023 | Report Code: OMR2025987 | Category : Pharmaceuticals | Delivery Format: /

The global neprilysin market is anticipated to grow at considerable CAGR during the forecast year. Neprilysin is a zinc-dependent metalloprotease that peptides with the amino side of hydrophobic residues, and inactivates various peptide hormones including neurotensin, oxytocin, bradykinin, glucagon, enkephalins, and substance P. Neprilysin is used in the neprilysin inhibitors, the medicines used for the treatment of high blood pressure, heart failures and Alzheimer’s disease. These medicines prevent the breakdown of natriuretic peptides. The major factor for the growth of the global neprilysin market is the increasing number of patients suffering from hypertension around the globe. According to a report published by World Health Org. (WHO) in 20221, the major cause of premature deaths is hypertension. An estimate of around 1.28 billion adults between the ages 30 years and 79 years suffer from hypertension. In addition, as per the same report, there are around 46% of adults with hypertension are unaware that they have the condition, less than 42% are diagnosed and treated. Thus, an increasing number of hypertension patients is driving the demand for neprilysin for the treatment of hypertension. Resulting in the growth of the global neprilysin market.

Impact of COVID-19 on Global Neprilysin Market

COVID-19 has impacted the global economy due to a slowdown in the manufacturing of various industries. During the COVID-19 lockdown, people are forced to change their living styles and eating habits. This sudden change in their daily schedule caused many of them with hypertension and acute heart failures. Due to increasing mortalities during the COVID-19 pandemic, the number of hypertension patients increased. Thus, increasing the demand for neprilysin for the treatment of hypertension.

Segmental Outlook

The global neprilysin market is segmented based on type and application. Based on type, the market is sub-segmented into TD-0714, sacubitril, PL-265, STR-324, and LHW-090. Based on application, the market is sub-segmented into acute heart failure, cancer pain, hypertension, and Alzheimer’s disease. Among these, the sacubitril type segment is expected to hold a prominent share in the global neprilysin market due to increasing cases of heart failure. Thus, increasing the demand for sacubitril neprilysin for the treatment of heart failures.

Global Neprilysin Market by Application, 2021(%) 

 Global Neprilysin Market by Application

The Alzheimer’s Disease Segment is Anticipated to Hold a Major Share in the Global Neprilysin market.

The neprilysin application for the Alzheimer’s disease segment is expected to hold a major share in the global neprilysin market due to increasing cases of Alzheimer’s disease globally. Alzheimer’s disease is a neurological disorder in which the brain gets shrink and brain cells die. There are several effects a person has to face due to Alzheimer’s disease including loss of memory and confusion in doing other mental activities. The increasing number of Alzheimer’s disease patients is expected to grow the segment in the global neprilysin market. According to an article published by Bright Focus Foundation on July 14, 2021, around 50 million people had Alzheimer’s disease. The number of patients suffering from Alzheimer’s disease is increasing and are expected to exceed 152 million by 2050.

Regional Outlooks

The global Neprilysin market is further segmented based on geography including North America (the US, and Canada), Europe (Italy, Spain, Germany, France, and Others), Asia-Pacific (India, China, Japan, South Korea, and Others), and the Rest of the World (the Middle East & Africa, and Latin America). The North American region is expected to hold the major share in the global Neprilysin market due to the presence of several key players in the region.

Global Neprilysin Market Growth by Region, 2022-2028 

Global Neprilysin Market Growth by Region

The Asia Pacific Region is Expected to Grow at a Significant CAGR among the Global Neprilysin Market During Forecast Year.

The Asia Pacific regional neprilysin market is anticipated to grow at a significant CAGR during the forecast year due to the increasing number of people with cancer. Neprilysin is used for the treatment of cancer pain. The increasing number of cancer patients in Asia Pacific countries such as India has increased the demand for the neprilysin in the region. According to a report published on JCO Global Oncology by National Cancer Registry Programme, India, there were around 1.39 million new patients diagnosed with cancer in 2020. This increasing number of cancer patients in the region is expected to drive the growth of the Asia Pacific regional neprilysin market.

Market Players Outlook

The major companies serving the global Neprilysin market include Merck Group, GlaxoSmithKline plc, Cipla Ltd., Novartis International AG, Pharmaleads SA, and many others. The market players are considerably contributing to the market growth by the adoption of various strategies including mergers & acquisitions, collaborations, fundings, and new product launches. For instance, in February 2021, Novartis International AG got approval from the US Food and Drug Administration (FDA) for the ‘Entresto’. Entresto is the medicine containing sacubitril neprilysin inhibitors valsartan angiotensin receptor blocker, that can be used for the reduction of risk of death from heart failures in adults. 

The Report Covers

  • Market value data analysis of 2021 and forecast to 2028.
  • Annualized market revenues ($ million) for each market segment.
  • Country-wise analysis of major geographical regions.
  • Key companies operating in the global neprilysin market. Based on the availability of data, information related to new product launches, and relevant news is also available in the report.
  • Analysis of business strategies by identifying the key market segments positioned for strong growth in the future.
  • Analysis of market entry and market expansion strategies.
  • Competitive strategies by identifying ‘who-stands-where’ in the market

1. Report Summary

  • Current Industry Analysis and Growth Potential Outlook
  • Impact of COVID-19 on The Global Neprilysin Market
  • Recovery Scenario of Global Neprilysin Market

1.1. Research Methods and Tools

1.2. Market Breakdown

1.2.1. By Segments

1.2.2. BY Region

2. Market Overview and Insights

2.1. Scope of the Report

2.2. Analyst Insight & Current Market Trends

2.2.1. Key Findings

2.2.2. Recommendations

2.2.3. Conclusion

3. Competitive Landscape

3.1. Cipla Ltd.

3.1.1. Overview

3.1.2. Financial Analysis 

3.1.3. SWOT Analysis

3.1.4. Recent Developments

3.2. GlaxoSmithKline plc.

3.2.1. Overview

3.2.2. Financial Analysis 

3.2.3. SWOT Analysis

3.2.4. Recent Developments

3.3. Merck Group

3.3.1. Overview

3.3.2. Financial Analysis 

3.3.3. SWOT Analysis

3.3.4. Recent Developments

3.4. Novartis International AG

3.4.1. Overview

3.4.2. Financial Analysis 

3.4.3. SWOT Analysis

3.4.4. Recent Developments

3.5. Pharmaleads SA

3.5.1. Overview

3.5.2. Financial Analysis 

3.5.3. SWOT Analysis

3.5.4. Recent Developments

3.6. Key Strategy Analysis

3.7. Impact of Covid-19 on Key Players

4. Market Segmentation

4.1. Global Neprilysin Market by Type

4.1.1. TD-0714

4.1.2. Sacubitril

4.1.3. PL-265

4.1.4. STR-324

4.1.5. LHW-090

4.2. Global Neprilysin Market by Application

4.2.1. Acute Heart Failure

4.2.2. Cancer Pain

4.2.3. Hypertension

4.2.4. Alzheimer’s Disease

5. Regional Analysis

5.1. North America

5.1.1. The US

5.1.2. Canada

5.2. Europe

5.2.1. UK

5.2.2. Germany

5.2.3. Italy

5.2.4. Spain

5.2.5. France

5.2.6. Rest of Europe 

5.3. Asia-Pacific

5.3.1. China

5.3.2. India

5.3.3. Japan

5.3.4. South Korea

5.3.5. Rest of Asia-Pacific 

5.4. Rest of the World

6. Company Profiles 

6.1. Abbott

6.2. AstraZeneca group Co.

6.3. BIOPROJET

6.4. Bristol Myers Squibb (BMS)

6.5. Eli Lilly and Co.

6.6. Oceanic Pharmachem Pvt. Ltd.

6.7. Pfizer Inc.

6.8. Purdue Pharma L.P.

6.9. Takeda Pharmaceuticals Co. Ltd.

6.10. Theravance Biopharma

6.11. Viatris Inc.

1. GLOBAL NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY TYPE, 2021-2028 ($ MILLION)

2. GLOBAL TD-0714 NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)

3. GLOBAL SACUBITRIL NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)

4. GLOBAL PL-265 NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)

5. GLOBAL STR-324 NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)

6. GLOBAL LHW-090 NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)

7. GLOBAL NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY APPLICATION, 2021-2028 ($ MILLION)

8. GLOBAL NEPRILYSIN FOR ACUTE HEART FAILURE MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)

9. GLOBAL NEPRILYSIN FOR CANCER PAIN MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)

10. GLOBAL NEPRILYSIN FOR HYPERTENSION MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)

11. GLOBAL NEPRILYSIN FOR ALZHEIMER’S DISEASE MARKET RESEARCH AND ANALYSIS BY REGION, 2021-2028 ($ MILLION)

12. GLOBAL NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY GEOGRAPHY, 2021-2028 ($ MILLION)

13. NORTH AMERICAN NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2021-2028 ($ MILLION)

14. NORTH AMERICAN NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY TYPE, 2021-2028 ($ MILLION)

15. NORTH AMERICAN NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY APPLICATION, 2021-2028 ($ MILLION)

16. EUROPEAN NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2021-2028 ($ MILLION)

17. EUROPEAN NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY TYPE, 2021-2028 ($ MILLION)

18. EUROPEAN NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY APPLICATION, 2021-2028 ($ MILLION)

19. ASIA-PACIFIC NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2021-2028 ($ MILLION)

20. ASIA-PACIFIC NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY TYPE, 2021-2028 ($ MILLION)

21. ASIA-PACIFIC NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY APPLICATION, 2021-2028 ($ MILLION)

22. REST OF THE WORLD NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2021-2028 ($ MILLION)

23. REST OF THE WORLD NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY TYPE, 2021-2028 ($ MILLION)

24. REST OF THE WORLD NEPRILYSIN MARKET RESEARCH AND ANALYSIS BY APPLICATION, 2021-2028 ($ MILLION)

1. IMPACT OF COVID-19 ON GLOBAL NEPRILYSIN MARKET, 2021-2028 ($ MILLION)

2. IMPACT OF COVID-19 ON GLOBAL NEPRILYSIN MARKET BY SEGMENT, 2021-2028 ($ MILLION)

3. RECOVERY OF GLOBAL NEPRILYSIN MARKET, 2021-2028 (%)

4. GLOBAL NEPRILYSIN MARKET SHARE BY TYPE, 2021 VS 2028 (%)

5. GLOBAL TD-0714 NEPRILYSIN MARKET SHARE BY GEOGRAPHY, 2021 VS 2028 (%)

6. GLOBAL SACUBITRIL NEPRILYSIN MARKET SHARE BY GEOGRAPHY, 2021 VS 2028 (%)

7. GLOBAL PL-265 NEPRILYSIN MARKET SHARE BY GEOGRAPHY, 2021 VS 2028 (%)

8. GLOBAL STR-324 NEPRILYSIN MARKET SHARE BY GEOGRAPHY, 2021 VS 2028 (%)

9. GLOBAL LHW-090 NEPRILYSIN MARKET SHARE BY GEOGRAPHY, 2021 VS 2028 (%)

10. GLOBAL NEPRILYSIN MARKET SHARE BY APPLICATION, 2021 VS 2028 (%)

11. GLOBAL NEPRILYSIN FOR ACUTE HEART FAILURE MARKET SHARE BY GEOGRAPHY, 2021 VS 2028 (%)

12. GLOBAL NEPRILYSIN FOR CANCER PAIN MARKET SHARE BY GEOGRAPHY, 2021 VS 2028 (%)

13. GLOBAL NEPRILYSIN FOR HYPERTENSION MARKET SHARE BY GEOGRAPHY, 2021 VS 2028 (%)

14. GLOBAL NEPRILYSIN FOR ALZHEIMER’S DISEASE MARKET SHARE BY GEOGRAPHY, 2021 VS 2028 (%)

15. GLOBAL NEPRILYSIN MARKET SHARE BY GEOGRAPHY, 2021 VS 2028 (%)

16. US NEPRILYSIN MARKET SIZE, 2021-2028 ($ MILLION)

17. CANADA NEPRILYSIN MARKET SIZE, 2021-2028 ($ MILLION)

18. UK NEPRILYSIN MARKET SIZE, 2021-2028 ($ MILLION)

19. FRANCE NEPRILYSIN MARKET SIZE, 2021-2028 ($ MILLION)

20. GERMANY NEPRILYSIN MARKET SIZE, 2021-2028 ($ MILLION)

21. ITALY NEPRILYSIN MARKET SIZE, 2021-2028 ($ MILLION)

22. SPAIN NEPRILYSIN MARKET SIZE, 2021-2028 ($ MILLION)

23. REST OF EUROPE NEPRILYSIN MARKET SIZE, 2021-2028 ($ MILLION)

24. INDIA NEPRILYSIN MARKET SIZE, 2021-2028 ($ MILLION)

25. CHINA NEPRILYSIN MARKET SIZE, 2021-2028 ($ MILLION)

26. JAPAN NEPRILYSIN MARKET SIZE, 2021-2028 ($ MILLION)

27. SOUTH KOREA NEPRILYSIN MARKET SIZE, 2021-2028 ($ MILLION)

28. REST OF ASIA-PACIFIC NEPRILYSIN MARKET SIZE, 2021-2028 ($ MILLION)

29. REST OF THE WORLD NEPRILYSIN MARKET SIZE, 2021-2028 ($ MILLION)