Preparative and process chromatography market is growing significantly at a CAGR of 6.2% during the forecast period. Chromatography is referred to as the process of separation of the mixture in which the mixture is passed through two phases i.e. mobile phase and stationary phase. The fluid is dissolved into the fluid (mobile phase) and passed through another material (stationary phase) and the constituents of the mixture travel at different speeds, resulting in the separation of the components. The preparative chromatography involves the isolation and purification of the specific substance from the sample, whereas, process chromatography involves the separation of the component of the sample. Moreover, mixtures that are being subjected to separation may be aqueous (soluble in water) and non-aqueous (soluble in oil, paint or any other solvent). 

Preparative and process chromatography finds its applications in various fields such as synthetic chemistry for the fingerprinting of peptides, proteins, and oligonucleotides, in cosmetics for the detection of flavors and fragrances or odoriferous substances and in environmental chemistry, pharmaceuticals, and food industry. The increasing prevalence of appendicitis along with the rising investment in biotechnology and pharmaceuticals industry by major players tends to drive the preparative and process chromatography market. However, the with the improvements in chromatography products, the inclusion of modern technologies have led the increase overall cost of the product resulting in the manufacturer’s preference for alternate separation techniques which may hinder the growth of the market. 

Segmental Outlook  

The preparative and process chromatography market is segmented on the basis of type and end-user. Based on the type, the market is segmented into preparative and process chromatography. Based on end-user, the market is segmented into biotechnology and pharmaceutical companies, food and nutrition industry, research institutes and laboratories, and others which include government. The government uses preparative and process chromatography for environmental testing and forensic testing.

Preparative and Process Chromatography Market Share by Type, 2018(%)

Preparative chromatography segment is estimated to have a significant market size

Preparative chromatography segment is expected to register significant market share over the forecast period owing to the preferred solution for the purification of small drugs and valuable chemical components at the <10 kg-level. Technological improvement in computer technology along with the development of nonchiral and chiral stationary phases have surged the demand for preparative chromatography. Preparative chromatography finds its application in various industry verticals such as pharmaceutical, biotechnology, biomedical, energy, food & cosmetics along with many others. Moreover, favorable government initiatives to modernize the regulation guidelines of pharmaceutical manufacturing is also driving the market growth. Additionally, the increasing demand for liquid preparative chromatography techniques has accelerated the demand for preparative chromatography. 

Significant application in forensic science 

Application of preparative and process chromatography in forensic testing is growing owing to the collection and analysis of evidence pertaining to a court case or an investigation. Chromatography is used in forensic science for the separation of compounds. Various types of chromatography techniques are involved in forensic testing such as planar chromatography, high-performance liquid chromatography (HPLC), and gas chromatography. Basic planar chromatography is used to identify two identical ink samples. Planar chromatography is further used to identify the stolen money by detecting the ink on the thief's hands. 

HPLC is used to analyze explosives as a different substance used in explosives will have different retention times. Various drugs are also detected with the help of HPLC resulting in the increased demand for preparative and process chromatography in forensic tests. Gas chromatography is used to identify if the deceased person has consumed any alcohol or drugs prior to death as well as samples from the crime scene such as blood and fibers from clothes can also be analyzed to further aid the investigation. 

Regional Outlook 

Moreover, the preparative and process chromatography market is further classified based on geography including North America, Europe, Asia-Pacific and Rest of the World (RoW). North America is expected to register significant growth over the forecast period owing to rising investment by major players towards research & development programs in the region. Presence of major players in the region tends to increase the market share of preparative and process chromatography in North America. Moreover, technological improvement in biotechnology research along with the favorable government initiatives has led to the increasing demand for preparative and process chromatography. 

Preparative and Process Chromatography Market Growth, by Region 2019-2025

• In October 2018, Servier has launched InnoPreP, a new preparative chromatography service offered under its contract development and manufacturing business. The new service offered the company to extend the company’s geographical outreach. 

The Report Covers

• Market value data analysis of 2018 and forecast to 2025.
• Annualized market revenues ($ million) for each market segment.
• Country-wise analysis of major geographical regions.
• Key companies operating in the global preparative and process chromatography market. Based on the availability of data, information related to pipeline products, and relevant news is also available in the report.
• Analysis of business strategies by identifying the key market segments positioned for strong growth in the future.
• Analysis of market-entry and market expansion strategies.
• Competitive strategies by identifying ‘who-stands-where’ in the market.