Protein Stability Analysis Market

Protein Stability Analysis Market Size, Share & Trends Analysis Report, By Technique (Spectroscopy, Chromatography, Differential Scanning Calorimetry, Differential Scanning Fluorimetry, Surface Plasmon Resonance and Other Techniques), By Product (Instruments, Accessories and Consumables and Software), By End-User (Pharmaceutical and Biotechnology Companies, Contract Research Organizations (CROs) and Research Institutes) and Forecast 2019-2025
    Update Available - Forecast 2024-2030   

Published: Jul 2023 | Report Code: OMR2020001 | Category : Biotechnology | Delivery Format: /

The global protein stability analysis market is estimated to grow at a CAGR of 8.4% during the forecast period. The major factors encouraging the growth of the market include the significant rise in pharmaceutical R&D programs and the emerging role of bioinformatics software in life science researches. There is an increasing pharmaceutical R&D across countries, such as the US, Europe, and China. For instance, as per the European Federation of Pharmaceutical Industries and Associations (EFPIA), the pharmaceutical R&D was $33.9 billion in 2016, whereas, in 2015, it was $33.4 billion and $27.9 billion in 2010. These researches play a vital role in the development of new drugs and vaccines for the prevention and treatment of multiple conditions. Such a rise in pharmaceutical R&D is promoting the drug discovery activities, which in turn, in contributing to the demand for protein stability analysis methods. 

Protein stability is usually determined with spectroscopy, differential scanning fluorimetry (DSF) and differential scanning calorimeter (DSC). Several thermal shift analysis processes involve the use of spectroscopy to assess protein stability. Typical applications have comprised observing the helix-coil transition in proteins upon thermal denaturation to monitor the effects that buffers, including sodium chloride or sodium acetate. This, in turn, is useful to determine the stability of proteins in a sample and thereby is leading to support drug discovery process. Apart from these, certain factors are restricting the market growth which includes stringent government regulations and high cost of protein stability analysis equipment.

Market Segmentation

The global protein stability analysis market is segmented based on technique, product, and end-user. Based on technique, the market is classified into spectroscopy, chromatography, DSC, DSF, surface plasmon resonance and other techniques. Based on the product, the market is classified into instruments, accessories and consumables and software. Based on the end-user, the market is classified into pharmaceutical and biotechnology companies, contract research organizations (CROs) and research institutes.

Pharmaceutical and Biotechnology Companies Have Led a Significant Share in the End-User Segment

Pharmaceutical and biotechnology companies are anticipated to hold a significant share in the market in 2018. This is resulting owing to the increasing presence of pharmaceutical and biotechnology companies which is contributing to the rise in drug discoveries across the countries. Moreover, increasing R&D investment by these companies are strengthening market growth. In Europe, Germany, UK, and France are some of the major R&D hubs in the biotech industry. These economies deploy modern research methodologies in the biotech research; thus, a shift is being observed towards advanced protein stability analysis instruments in the pharmaceutical and biotechnology companies. Increasing focus on personalized medicine by these companies are supporting to drive market growth.

Global Protein Stability Analysis Market Share by End-User, 2018 (%)

Global Protein Stability Analysis Market Share by End-User

Regional Outlook

The global protein stability analysis market is segmented based on four major regions, including North America, Europe, Asia-Pacific and the Rest of the world (RoW). In 2018, North America has shown significant growth in the market coupled with the presence of major players, such as Thermo Fisher Scientific, Inc., Agilent Technologies, Inc., and General Electric Co. Additionally, the availability of a wide range of biotech and life science players and their significant contribution are fueling the growth of the market.

Global Protein Stability Analysis Market Growth, by Region 2019-2025

Global Protein Stability Analysis Market Growth, by Region

Asia-Pacific is Estimated to Witness Considerable Growth During the Forecast Period

The rising number of CROs and research institutions are supporting to drive the demand for protein stability analysis instruments in the region. The Chinese economy is becoming an R&D concentrated economy in every sector, primarily in the pharmaceutical industry. The demand for outsourcing services for the pharmaceutical industry is rising in China owing to the regulatory changes and continuously growing start-ups in the healthcare industry in the country. The pharmaceutical business in China works under the Marketing Authorization Holder (MAH) pilot program. Under this program, the contract manufacturing organizations (CMOs) are providing support to the pharma organizations in the field of R&D and other related manufacturing operations. The program further ensures the production and delivery of high-quality and effective medicines. Therefore, the government is facilitating the use of CMOS as these organizations support for R&D and production process of drugs and vaccines, which in turn, is contributing to the market growth.

Market Players Outlook

The major companies in the market include Thermo Fisher Scientific, Inc., Agilent Technologies, Inc., General Electric Co., Shimadzu Corp., and Waters Corp. The strategies followed by the market players include mergers and acquisitions, product launches, partnerships and collaborations and geographical expansion to increase market share and gain a competitive advantage over their competitors. For instance, in April 2019, Thermo Fisher Scientific, Inc. declared a collaborative research project for the development of advanced end-to-end workflows for the preparation, monitoring, and characterization of new and complex biotherapeutics with the use of liquid chromatography-mass spectrometry (LC-MS). Moreover, in January 2018, Horiba Scientific acquired AIST-NT, a provider of advanced integrated spectroscopy technology. The integration of AIST-NT’S advanced scanning probe microscopy technology with Horiba’s cutting-edge Raman technology will allow the Horiba to strengthen its position in NanoRaman spectroscopy. 

The Report Covers

  • Market value data analysis of 2018 and forecast to 2025.
  • Annualized market revenues ($ million) for each market segment.
  • Country-wise analysis of major geographical regions.
  • Key companies operating in the global protein stability analysis market. Based on the availability of data, information related to pipeline products, and relevant news is also available in the report.
  • Analysis of business strategies by identifying the key market segments positioned for strong growth in the future.
  • Analysis of market-entry and market expansion strategies.
  • Competitive strategies by identifying ‘who-stands-where’ in the market.

1. Report Summary

1.1. Research Methods and Tools

1.2. Market Breakdown

1.2.1. By Segments

1.2.2. By Geography

2. Market Overview and Insights

2.1. Scope of the Report

2.2. Analyst Insight & Current Market Trends

2.2.1. Key Findings

2.2.2. Recommendations

2.2.3. Conclusion

2.3. Rules & Regulations

3. Competitive Landscape

3.1. Company Share Analysis

3.2. Key Strategy Analysis

3.3. Key Company Analysis

3.3.1. Thermo Fisher Scientific, Inc.

3.3.1.1. Overview

3.3.1.2. Financial Analysis

3.3.1.3. SWOT Analysis

3.3.1.4. Recent Developments

3.3.2. Agilent Technologies, Inc.

3.3.2.1. Overview

3.3.2.2. Financial Analysis

3.3.2.3. SWOT Analysis

3.3.2.4. Recent Developments

3.3.3. General Electric Co.

3.3.3.1. Overview

3.3.3.2. Financial Analysis

3.3.3.3. SWOT Analysis

3.3.3.4. Recent Developments

3.3.4. Shimadzu Corp.

3.3.4.1. Overview

3.3.4.2. Financial Analysis

3.3.4.3. SWOT Analysis

3.3.4.4. Recent Developments

3.3.5. Waters Corp.

3.3.5.1. Overview

3.3.5.2. Financial Analysis

3.3.5.3. SWOT Analysis

3.3.5.4. Recent Developments

4. Market Determinants 

4.1 Motivators

4.2 Restraints

4.3 Opportunities 

5. Market Segmentation

5.1. Global Protein Stability Analysis Market by Technique

5.1.1. Spectroscopy

5.1.2. Chromatography

5.1.3. Differential Scanning Calorimetry (DSC)

5.1.4. Differential Scanning Fluorimetry (DSF)

5.1.5. Surface Plasmon Resonance

5.1.6. Others (Pulse-Chase)

5.2. Global Protein Stability Analysis Market by Product

5.2.1. Instruments

5.2.2. Accessories and Consumables

5.2.3. Software

5.3. Global Protein Stability Analysis Market by End-User

5.3.1. Pharmaceutical and Biotechnology Companies

5.3.2. Contract Research Organizations

5.3.3. Research Institutions

6. Regional Analysis

6.1. North America

6.1.1. United States

6.1.2. Canada

6.2. Europe

6.2.1. UK

6.2.2. Germany

6.2.3. Italy

6.2.4. Spain

6.2.5. France

6.2.6. Rest of Europe 

6.3. Asia-Pacific

6.3.1. China

6.3.2. India

6.3.3. Japan

6.3.4. Rest of Asia-Pacific 

6.4. Rest of the World

7. Company Profiles

7.1. Agilent Technologies, Inc.

7.2. ATA Scientific Pty. Ltd.

7.3. Biogenuix Medsystems Pvt. Ltd.

7.4. Biotium Inc.

7.5. Cyrus Biotechnology, Inc.

7.6. Enzo Biochem, Inc.

7.7. Epiphyte Three, Inc.

7.8. General Electric Co.

7.9. Geno Technology, Inc.

7.10. HORIBA, Ltd.

7.11. Illumina, Inc.

7.12. Malvern Panalytical, Ltd. (A Spectris PLC Company)

7.13. Merck KGaA

7.14. Molecular Dimensions, Ltd. (CalibreScientific Holdings)

7.15. NanoTemper Technologies GmbH

7.16. PerkinElmer, Inc.

7.17. SETARAM Instrumentation (KEP Technologies group)

7.18. Shimadzu Corp.

7.19. Thermo Fisher Scientific, Inc.

7.20. Waters Corp.

7.21. Wyatt Technology Corp.

1. GLOBAL PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY TECHNIQUE, 2018-2025 ($ MILLION)

2. GLOBAL SPECTROSCOPY MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)

3. GLOBAL CHROMATOGRAPHY MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)

4. GLOBAL DSC MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)

5. GLOBAL DSF MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)

6. GLOBAL SURFACE PLASMON RESONANCE  MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)

7. GLOBAL OTHER TECHNOLOGIES MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)

8. GLOBAL PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY PRODUCT, 2018-2025 ($ MILLION)

9. GLOBAL PROTEIN STABILITY ANALYSIS INSTRUMENTS MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)

10. GLOBAL PROTEIN STABILITY ANALYSIS ACCESSORIES AND CONSUMABLES MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)

11. GLOBAL PROTEIN STABILITY ANALYSIS SOFTWARE MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)

12. GLOBAL PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY END-USER, 2018-2025 ($ MILLION)

13. GLOBAL PROTEIN STABILITY ANALYSIS IN PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)

14. GLOBAL PROTEIN STABILITY ANALYSIS IN CONTRACT RESEARCH ORGANIZATIONS (CROs) MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)

15. GLOBAL PROTEIN STABILITY ANALYSIS IN RESEARCH INSTITUTIONS  MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)

16. GLOBAL PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY GEOGRAPHY, 2018-2025 ($ MILLION)

17. NORTH AMERICAN PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2018-2025 ($ MILLION)

18. NORTH AMERICAN PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY TECHNIQUE, 2018-2025 ($ MILLION)

19. NORTH AMERICAN PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY PRODUCT, 2018-2025 ($ MILLION)

20. NORTH AMERICAN PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY END-USER, 2018-2025 ($ MILLION)

21. EUROPEAN PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY TECHNIQUE, 2018-2025 ($ MILLION)

22. EUROPEAN PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY PRODUCT, 2018-2025 ($ MILLION)

23. EUROPEAN PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY END-USER, 2018-2025 ($ MILLION)

24. ASIA-PACIFIC PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2018-2025 ($ MILLION)

25. ASIA-PACIFIC PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY TECHNIQUE, 2018-2025 ($ MILLION)

26. ASIA-PACIFIC PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY PRODUCT, 2018-2025 ($ MILLION)

27. ASIA-PACIFIC PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY END-USER, 2018-2025 ($ MILLION)

28. REST OF THE WORLD PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY TECHNIQUE, 2018-2025 ($ MILLION)

29. REST OF THE WORLD PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY PRODUCT, 2018-2025 ($ MILLION)

30. REST OF THE WORLD PROTEIN STABILITY ANALYSIS MARKET RESEARCH AND ANALYSIS BY END-USER, 2018-2025 ($ MILLION)

1. GLOBAL PROTEIN STABILITY ANALYSIS MARKET SHARE BY TECHNIQUE, 2018 VS 2025 (%)

2. GLOBAL PROTEIN STABILITY ANALYSIS MARKET SHARE BY PRODUCT, 2018 VS 2025 (%)

3. GLOBAL PROTEIN STABILITY ANALYSIS MARKET SHARE BY END-USER, 2018 VS 2025 (%)

4. GLOBAL PROTEIN STABILITY ANALYSIS MARKET SHARE BY GEOGRAPHY, 2018 VS 2025 (%)

5. US PROTEIN STABILITY ANALYSIS MARKET SIZE, 2018-2025 ($ MILLION)

6. CANADA PROTEIN STABILITY ANALYSIS MARKET SIZE, 2018-2025 ($ MILLION)

7. UK PROTEIN STABILITY ANALYSIS MARKET SIZE, 2018-2025 ($ MILLION)

8. FRANCE PROTEIN STABILITY ANALYSIS MARKET SIZE, 2018-2025 ($ MILLION)

9. GERMANY PROTEIN STABILITY ANALYSIS MARKET SIZE, 2018-2025 ($ MILLION)

10. ITALY PROTEIN STABILITY ANALYSIS MARKET SIZE, 2018-2025 ($ MILLION)

11. SPAIN PROTEIN STABILITY ANALYSIS MARKET SIZE, 2018-2025 ($ MILLION)

12. ROE PROTEIN STABILITY ANALYSIS MARKET SIZE, 2018-2025 ($ MILLION)

13. INDIA PROTEIN STABILITY ANALYSIS MARKET SIZE, 2018-2025 ($ MILLION)

14. CHINA PROTEIN STABILITY ANALYSIS MARKET SIZE, 2018-2025 ($ MILLION)

15. JAPAN PROTEIN STABILITY ANALYSIS MARKET SIZE, 2018-2025 ($ MILLION)

16. REST OF ASIA-PACIFIC PROTEIN STABILITY ANALYSIS MARKET SIZE, 2018-2025 ($ MILLION)

17. REST OF THE WORLD PROTEIN STABILITY ANALYSIS MARKET SIZE, 2018-2025 ($ MILLION)